Product details

Anti-PRKAA2 Antibody

Catalog number M01420-80ul

Price for M01420-80ul

Size / count 80 µL

About this product

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M01420-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Gene Name: PRKAA2
UniProt: P54646
Host: Mouse
Reactivity: Human
Immunogen: This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Clonality: Monoclonal
Clone: Clone: 206CT5.4.2
Applications: IF, WB
Field of Research: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Autophagy
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 1730797117712357173079711771235717307971177123577959015340777572568757111554766115186991586617117711846181849301465184920160076212056413673262437079666212056412856106632029622174860971251974520074060
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 62320 Da
Subcellular Location: Cytoplasm {ECO:0000250|UniProtKB:Q8BRK8}. Nucleus. Note=In response to stress, recruited by p53/TP53 to specific promoters.
Isotype: IgG2a, K
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PRKAA2 Antibody?

The catalog number for Anti-PRKAA2 Antibody is M01420-80ul.

What sizes are available for Anti-PRKAA2 Antibody?

Anti-PRKAA2 Antibody is available in the following size(s): 80 µL.

Is Anti-PRKAA2 Antibody in stock?

Anti-PRKAA2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PRKAA2 Antibody?

The safety data sheet for Anti-PRKAA2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01420.

What is Anti-PRKAA2 Antibody used for?

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.