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Product details

Anti-PRKAA2 Antibody

Catalog number M01420-400ul

Price for M01420-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
M01420-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Synonyms
5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2, AMPK, AMPK2
Gene Name
PRKAA2
UniProt
P54646
Host
Mouse
Reactivity
Human
Immunogen
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
Clonality
Monoclonal
Clone
Clone: 206CT5.4.2
Applications
IF, WB
Field of Research
Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Autophagy
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
1730797117712357173079711771235717307971177123577959015340777572568757111554766115186991586617117711846181849301465184920160076212056413673262437079666212056412856106632029622174860971251974520074060
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
62320 Da
Subcellular Location
Cytoplasm {ECO:0000250|UniProtKB:Q8BRK8}. Nucleus. Note=In response to stress, recruited by p53/TP53 to specific promoters.
Isotype
IgG2a, K
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PRKAA2 Antibody?

The catalog number for Anti-PRKAA2 Antibody is M01420-400ul.

What sizes are available for Anti-PRKAA2 Antibody?

Anti-PRKAA2 Antibody is available in the following size(s): 400 µL.

Is Anti-PRKAA2 Antibody in stock?

Anti-PRKAA2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PRKAA2 Antibody?

The safety data sheet for Anti-PRKAA2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01420.

What is Anti-PRKAA2 Antibody used for?

Boster Bio Anti-PRKAA2 Antibody (Catalog # M01420) . Tested in IF, WB application (s) . This antibody reacts with Human.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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