Product details

Anti-MBD2 Antibody

Catalog number M01746-1-50ul

Price for M01746-1-50ul

Size / count 50 µL

About this product

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: M01746-1-50ul
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Synonyms: Methyl-CpG-binding domain protein 2, Demethylase, DMTase, Methyl-CpG-binding protein MBD2, MBD2
Gene Name: MBD2
UniProt: Q9UBB5
Host: Mouse
Reactivity: Human
Immunogen: This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
Clonality: Monoclonal
Clone: Clone: 1812CT625.9.45
Tissue Specificity: Highly expressed in brain, heart, kidney, stomach, testis and placenta.
Applications: WB, IHC-P
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 97746691094785224307175104714991094785216428440289776661047149910947852164151791641517912665568
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 43255 Da
Subcellular Location: Nucleus. Chromosome Note=Nuclear, in discrete foci (PubMed:12183469) . Detected at replication foci in late S phase. Localizes to methylated chromatin (PubMed:16428440) . Localizes to sites of DNA damage in a manner partially dependent on ZMYND8 (PubMed:27732854)
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-MBD2 Antibody?

The catalog number for Anti-MBD2 Antibody is M01746-1-50ul.

What sizes are available for Anti-MBD2 Antibody?

Anti-MBD2 Antibody is available in the following size(s): 50 µL.

Is Anti-MBD2 Antibody in stock?

Anti-MBD2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MBD2 Antibody?

The safety data sheet for Anti-MBD2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01746-1.

What is Anti-MBD2 Antibody used for?

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.