Product details

Anti-MBD2 Antibody

Catalog number M01746-1-200ul

Price for M01746-1-200ul

Size / count 200 µL

About this product

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: M01746-1-200ul
Size / count: 200 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Synonyms: Methyl-CpG-binding domain protein 2, Demethylase, DMTase, Methyl-CpG-binding protein MBD2, MBD2
Gene Name: MBD2
UniProt: Q9UBB5
Host: Mouse
Reactivity: Human
Immunogen: This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
Clonality: Monoclonal
Clone: Clone: 1812CT625.9.45
Tissue Specificity: Highly expressed in brain, heart, kidney, stomach, testis and placenta.
Applications: WB, IHC-P
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 97746691094785224307175104714991094785216428440289776661047149910947852164151791641517912665568
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 43255 Da
Subcellular Location: Nucleus. Chromosome Note=Nuclear, in discrete foci (PubMed:12183469) . Detected at replication foci in late S phase. Localizes to methylated chromatin (PubMed:16428440) . Localizes to sites of DNA damage in a manner partially dependent on ZMYND8 (PubMed:27732854)
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-MBD2 Antibody?

The catalog number for Anti-MBD2 Antibody is M01746-1-200ul.

What sizes are available for Anti-MBD2 Antibody?

Anti-MBD2 Antibody is available in the following size(s): 200 µL.

Is Anti-MBD2 Antibody in stock?

Anti-MBD2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MBD2 Antibody?

The safety data sheet for Anti-MBD2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01746-1.

What is Anti-MBD2 Antibody used for?

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.