Anti-PP2A-alpha PPP2CA Monoclonal Antibody

About this product

Boster Bio Anti-PP2A-alpha PPP2CA Monoclonal Antibody catalog # M01893. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Bovine, Chicken, Dog, Pig, Rabbit, Zebrafish.

Specifications

Catalog number

M01893

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha;3.1.3.16; Replication protein C; RP-C; PPP2CA

Gene Name

PPP2CA

UniProt

P67775

Host

Mouse

Reactivity

Human, Mouse, Bovine, Chicken, Dog, Pig, Rabbit, Zebrafish

Immunogen

Purified recombinant human PP2A-Cα (N-terminus) protein fragments expressed in E.coli.

Clonality

Monoclonal

Applications

WB, IF

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

PP2A is the major phosphatase for microtubule-associated proteins (MAPs) . PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity) . Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

35594 MW

Gene Name Synonym

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Subcellular Location

Cytoplasm

Protein Name

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Contents

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.