Anti-Fibulin-5 FBLN5 Monoclonal Antibody

About this product

Boster Bio Anti-Fibulin-5 FBLN5 Monoclonal Antibody catalog # M02317. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number

M02317

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50; FBLN5; DANCE; UNQ184/PRO210

Gene Name

FBLN5

UniProt

Q9UBX5

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of Fibulin-5 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 3F10A5 / 3F8A12

Tissue Specificity

Expressed in skin fibroblasts (at protein level) (PubMed:17035250) . Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823) .

Applications

WB, IHC, IF, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537) . Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity) . Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823) . May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

50180 MW

Gene Name Synonym

Fibulin-5

Subcellular Location

Secreted

Protein Name

Fibulin-5

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.