Anti-ACO1 Antibody (N-Term)

About this product

Boster Bio Anti-ACO1 Antibody (N-Term) (Catalog # M02781-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M02781-1-200ul

Size / count

200 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

Synonyms

Cytoplasmic aconitate hydratase, Aconitase, 4.2.1.3, Citrate hydro-lyase, Ferritin repressor protein, Iron regulatory protein 1, IRP1, Iron-responsive element-binding protein 1, IRE-BP 1, ACO1, IREB1

Gene Name

ACO1

UniProt

P21399

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This ACO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 124-155 amino acids from human ACO1.

Clonality

Polyclonal

Applications

WB

Field of Research

Cardiovascular, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

98399 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cytoplasm, cytosol.

Prediction Reactivity

Rabbit

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.