Anti-XRN1 Antibody

Catalog number M02855-50ul

Price for M02855-50ul

Size / count 50 µL

About this product

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M02855-50ul
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Synonyms: 5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1
Gene Name: XRN1
UniProt: Q8IZH2
Host: Mouse
Reactivity: Human
Immunogen: This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.
Clonality: Monoclonal
Clone: Clone: 1647CT536.85.48
Tissue Specificity: Expressed in heart, brain, pancreas, spleen, testis, osteogenic sarcoma (OGS) biopsy and primary cell lines
Applications: WB
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 194107 Da
Applications Notes: WB: 1:2000
Subcellular Location: Cytoplasm. Note=Discrete foci at the inner surface of the cell membrane
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-XRN1 Antibody?

The catalog number for Anti-XRN1 Antibody is M02855-50ul.

What sizes are available for Anti-XRN1 Antibody?

Anti-XRN1 Antibody is available in the following size(s): 50 µL.

Is Anti-XRN1 Antibody in stock?

Anti-XRN1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-XRN1 Antibody?

The safety data sheet for Anti-XRN1 Antibody is available here: https://www.bosterbio.com/msds?sku=M02855.

What is Anti-XRN1 Antibody used for?

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.