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Product details

Anti-XRN1 Antibody

Catalog number M02855-200ul

Price for M02855-200ul

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Size / count 200 µL

About this product

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
M02855-200ul
Size / count
200 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Synonyms
5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1
Gene Name
XRN1
UniProt
Q8IZH2
Host
Mouse
Reactivity
Human
Immunogen
This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.
Clonality
Monoclonal
Clone
Clone: 1647CT536.85.48
Tissue Specificity
Expressed in heart, brain, pancreas, spleen, testis, osteogenic sarcoma (OGS) biopsy and primary cell lines
Applications
WB
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
194107 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cytoplasm. Note=Discrete foci at the inner surface of the cell membrane
Isotype
IgG1, k
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-XRN1 Antibody?

The catalog number for Anti-XRN1 Antibody is M02855-200ul.

What sizes are available for Anti-XRN1 Antibody?

Anti-XRN1 Antibody is available in the following size(s): 200 µL.

Is Anti-XRN1 Antibody in stock?

Anti-XRN1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-XRN1 Antibody?

The safety data sheet for Anti-XRN1 Antibody is available here: https://www.bosterbio.com/msds?sku=M02855.

What is Anti-XRN1 Antibody used for?

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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