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Product details

Anti-ITGA3 Antibody (N-term)

Catalog number M02902-1-80ul

Price for M02902-1-80ul

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Size / count 80 µL

About this product

Boster Bio Anti-ITGA3 Antibody (N-term) (Catalog # M02902-1) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
M02902-1-80ul
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Synonyms
Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD49c, Integrin alpha-3 heavy chain, Integrin alpha-3 light chain, ITGA3, MSK18
Gene Name
ITGA3
UniProt
P26006
Host
Rabbit
Reactivity
Human
Immunogen
This ITGA3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Clonality
Polyclonal
Tissue Specificity
Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells.
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha- 3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
116612 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid- anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-ITGA3 Antibody (N-term)?

The catalog number for Anti-ITGA3 Antibody (N-term) is M02902-1-80ul.

What sizes are available for Anti-ITGA3 Antibody (N-term)?

Anti-ITGA3 Antibody (N-term) is available in the following size(s): 80 µL.

Is Anti-ITGA3 Antibody (N-term) in stock?

Anti-ITGA3 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ITGA3 Antibody (N-term)?

The safety data sheet for Anti-ITGA3 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=M02902-1.

What is Anti-ITGA3 Antibody (N-term) used for?

Boster Bio Anti-ITGA3 Antibody (N-term) (Catalog # M02902-1) . Tested in WB application (s) . This antibody reacts with Human.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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