Anti-TNFRSF18 Mouse Monoclonal Antibody [Clone ID: OTI4A9]

About this product

Boster Bio TNFRSF18 mouse monoclonal antibody, clone OTI4A9 (formerly 4A9) . Catalog# M03125. Tested in FC, WB. This antibody reacts with Human.

Specifications

Catalog number

M03125

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene Name

TNFRSF18

UniProt

Q9Y5U5

Host

Mouse

Reactivity

Human

Immunogen

Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18 (NP_004186) produced in E.coli.

Clonality

Monoclonal

Clone

Clone: OTI4A9

Applications

Flow Cytometry, WB

Purification

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration

1 mg/mL

Storage Conditions

Store at -20°C as received.

Applications Notes

WB 1:2000

Isotype

IgG1

Contents

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Conjugate

Unconjugated