Anti-GSK alpha GSK3A Monoclonal Antibody — image 1 of 2

Product details

Anti-GSK alpha GSK3A Monoclonal Antibody

Catalog number M03152

Price for M03152

Size / count 100 µL

About this product

Boster Bio Anti-GSK alpha GSK3A Monoclonal Antibody catalog # M03152. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number: M03152
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Glycogen synthase kinase-3 alpha; GSK-3 alpha;2.7.11.26; Serine/threonine-protein kinase GSK3A;2.7.11.1; GSK3A
Gene Name: GSK3A
UniProt: P49840
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of GSK3α expressed in E. Coli.
Clonality: Monoclonal
Clone: Clone: 6G2F1 / 6G2F2
Applications: WB, IHC, IF, ELISA
Purification: Affinity purification
Concentration: 1 mg/mL
Form: Liquid
Function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 50981 MW
Gene Name Synonym: Glycogen synthase kinase-3 alpha
Protein Name: Glycogen synthase kinase-3 alpha
Contents: Ascitic fluid containing 0.03% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-GSK alpha GSK3A Monoclonal Antibody?

The catalog number for Anti-GSK alpha GSK3A Monoclonal Antibody is M03152.

What sizes are available for Anti-GSK alpha GSK3A Monoclonal Antibody?

Anti-GSK alpha GSK3A Monoclonal Antibody is available in the following size(s): 100 µL.

Is Anti-GSK alpha GSK3A Monoclonal Antibody in stock?

Anti-GSK alpha GSK3A Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GSK alpha GSK3A Monoclonal Antibody?

The safety data sheet for Anti-GSK alpha GSK3A Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M03152.

What is Anti-GSK alpha GSK3A Monoclonal Antibody used for?

Boster Bio Anti-GSK alpha GSK3A Monoclonal Antibody catalog # M03152. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.