Anti-SAFB-1 monoclonal Antibody

About this product

Boster Bio Anti-SAFB-1 monoclonal Antibody catalog # M03458. Tested in WB, ICC applications. This antibody reacts with Human.

Specifications

Catalog number

M03458

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein; SAFB; HAP, HET, SAFB1

Gene Name

SAFB

UniProt

Q15424

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length Human SAFB-1.

Clonality

Monoclonal

Tissue Specificity

Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.

Applications

WB, ICC

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity) . Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity) . Can inhibit cell proliferation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

102642 MW

Gene Name Synonym

Scaffold attachment factor B1

Subcellular Location

Nucleus

Protein Name

Scaffold attachment factor B1

Contents

Mouse IgG1, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2