Anti-GNMT Antibody (C-term)

About this product

Boster Bio Anti-GNMT Antibody (C-term) (Catalog # M03562) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number

M03562-200ul

Size / count

200 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy) . Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.

Synonyms

Glycine N-methyltransferase, 2.1.1.20, GNMT

Gene Name

GNMT

UniProt

Q14749

Host

Mouse

Reactivity

Human

Immunogen

This GNMT antibody is generated from a mouse immunized with a recombinant protein between 1-295 amino acids from the human GNMT.

Clonality

Monoclonal

Clone

Clone: 1041CT18.2.3

Tissue Specificity

Expressed only in liver, pancreas, and prostate.

Applications

WB, Flow Cytometry

Field of Research

Metabolism, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L- homocysteine.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

32742 Da

Subcellular Location

Cytoplasm {ECO:0000250|UniProtKB:P13255}.

Isotype

IgG2a, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.