Anti- (Mouse) Med15 Antibody (C-term)

About this product

Boster Bio Anti- (Mouse) Med15 Antibody (C-term) (Catalog # M03568-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Mouse, Rat.

Specifications

Catalog number

M03568-1-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity) .

Synonyms

Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15, Positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, mPcqap, Med15, Pcqap

Gene Name

Med15

UniProt

Q924H2

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

This mouse Med15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of mouse Med15.

Clonality

Polyclonal

Applications

WB, IHC-P

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol- dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

86607 Da

Subcellular Location

Cytoplasm. Nucleus.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.