Anti-WWP2 Antibody (N-term)

Catalog number M03634-80ul

Price for M03634-80ul

Size / count 80 µL

About this product

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M03634-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation- induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Synonyms: NEDD4-like E3 ubiquitin-protein ligase WWP2, 632-, Atrophin-1-interacting protein 2, AIP2, WW domain-containing protein 2, WWP2
Gene Name: WWP2
UniProt: O00308
Host: Rabbit
Reactivity: Human
Immunogen: This WWP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from the N-terminal region of human WWP2.
Clonality: Polyclonal
Tissue Specificity: Detected in heart, throughout the brain, placenta, lung, liver, muscle, kidney and pancreas. Also detected in spleen and peripheral blood leukocytes.
Applications: WB
Field of Research: Viral process, Host-Virus Interaction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T- cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 98912 Da
Applications Notes: WB: 1:1000
Subcellular Location: Nucleus
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-WWP2 Antibody (N-term)?

The catalog number for Anti-WWP2 Antibody (N-term) is M03634-80ul.

What sizes are available for Anti-WWP2 Antibody (N-term)?

Anti-WWP2 Antibody (N-term) is available in the following size(s): 80 µL.

Is Anti-WWP2 Antibody (N-term) in stock?

Anti-WWP2 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-WWP2 Antibody (N-term)?

The safety data sheet for Anti-WWP2 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=M03634.

What is Anti-WWP2 Antibody (N-term) used for?

Boster Bio Anti-WWP2 Antibody (N-term) (Catalog # M03634) . Tested in WB application (s) . This antibody reacts with Human.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.