Anti-RAB14 Antibody

About this product

Boster Bio Anti-RAB14 Antibody (Catalog # M04231) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

M04231-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity) . Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.

Synonyms

Ras-related protein Rab-14, RAB14

Gene Name

RAB14

UniProt

P61106

Host

Mouse

Reactivity

Human

Immunogen

This RAB14 antibody is generated from a mouse immunized with a recombinant protein of human RAB14.

Clonality

Monoclonal

Clone

Clone: 1779CT692.32.86

Applications

WB

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity) . Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

23897 Da

Applications Notes

WB: 1:2000

Subcellular Location

Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Note=Recruited to recycling endosomes by DENND6A (PubMed:22595670) . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) .

Prediction Reactivity

Chicken, Mouse

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.