Anti-EIF2A Antibody

About this product

Boster Bio Anti-EIF2A Antibody (Catalog # M04387-2) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M04387-2-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Synonyms

Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A

Gene Name

EIF2S1

UniProt

P05198

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.

Clonality

Monoclonal

Clone

Clone: 1763CT102.71.17

Applications

WB

Field of Research

Apoptosis

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

36112 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q6ZWX6}. Note=Colocalizes with NANOS3 in the stress granules. {ECO:0000250|UniProtKB:Q6ZWX6}

Isotype

IgG2b, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.