Anti-USP5 Antibody

Catalog number M04550-400ul

Price for M04550-400ul

Size / count 400 µL

About this product

Boster Bio Anti-USP5 Antibody (Catalog # M04550) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M04550-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Synonyms: Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, ISOT
Gene Name: USP5
UniProt: P45974
Host: Mouse
Reactivity: Human, Mouse, Rat
Immunogen: This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
Clonality: Monoclonal
Clone: Clone: 1340CT704.170.140
Applications: WB
Field of Research: Cell Biology
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys- 48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 95786 Da
Applications Notes: WB: 1:2000
Isotype: IgG1, κ
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-USP5 Antibody?

The catalog number for Anti-USP5 Antibody is M04550-400ul.

What sizes are available for Anti-USP5 Antibody?

Anti-USP5 Antibody is available in the following size(s): 400 µL.

Is Anti-USP5 Antibody in stock?

Anti-USP5 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-USP5 Antibody?

The safety data sheet for Anti-USP5 Antibody is available here: https://www.bosterbio.com/msds?sku=M04550.

What is Anti-USP5 Antibody used for?

Boster Bio Anti-USP5 Antibody (Catalog # M04550) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.