Anti-RAB1B Antibody

About this product

Boster Bio Anti-RAB1B Antibody (Catalog # M04589) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number

M04589-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.

Synonyms

Ras-related protein Rab-1B, RAB1B

Gene Name

RAB1B

UniProt

Q9H0U4

Host

Mouse

Reactivity

Human

Immunogen

This RAB1B antibody is generated from a mouse immunized with a recombinant protein between 1-201 amino acids from human RAB1B.

Clonality

Monoclonal

Clone

Clone: 1673CT667.16.73

Applications

WB, Flow Cytometry

Field of Research

Signal Transduction, Autophagy

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

20545908943700294370022054590826209634

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

22171 Da

Subcellular Location

Cytoplasm. Membrane; Lipid-anchor; Cytoplasmic side. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P10536}. Note=Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments (PubMed:11389151) . In the GDP-form, colocalizes with GDI in the cytoplasm (PubMed:11389151) . Co-localizes with MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment and to the peri- Golgi region (By similarity) . {ECO:0000250|UniProtKB:P10536, ECO:0000269|PubMed:11389151}

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.