Anti-STMN2 Antibody (Center)

About this product

Boster Bio Anti-STMN2 Antibody (Center) (Catalog # M04729) . Tested in WB, IHC, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number

M04729-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity) .

Synonyms

Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10

Gene Name

STMN2

UniProt

Q93045

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 82-116 amino acids from the Central region of human STMN2.

Clonality

Polyclonal

Tissue Specificity

Neuron specific.

Applications

WB, IHC, IF, Flow Cytometry

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

20828 Da

Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity) . Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.