Anti-SRGAP2 Antibody (C-term)

Catalog number M05125-50ul

Price for M05125-50ul

Size / count 50 µL

About this product

Boster Bio Anti-SRGAP2 Antibody (C-term) (Catalog # M05125) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: M05125-50ul
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
Synonyms: SLIT-ROBO Rho GTPase-activating protein 2, srGAP2, Formin-binding protein 2, Rho GTPase-activating protein 34, SRGAP2, ARHGAP34, FNBP2, KIAA0456, SRGAP2A
Gene Name: SRGAP2
UniProt: O75044
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: This SRGAP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1040-1071amino acids from the C-terminal region of human SRGAP2.
Clonality: Polyclonal
Applications: WB
Field of Research: Neuroscience, Signal Transduction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 2081065327373832283332122255994427373832273738322081065321148482
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 120871 Da
Applications Notes: WB: 1:2000
Subcellular Location: Cell membrane. Cell projection, dendritic spine. Postsynaptic density {ECO:0000250|UniProtKB:Q91Z67}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q91Z67}. Cell projection, lamellipodium. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q91Z67}. Nucleus {ECO:0000250|UniProtKB:D4A208} Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q91Z67}. Note=Recruited to actin-rich phagosomes during phagocytosis (By similarity) . Translocates from nucleus to cytoplasm during development (By similarity) {ECO:0000250|UniProtKB:D4A208, ECO:0000250|UniProtKB:Q91Z67}
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-SRGAP2 Antibody (C-term)?

The catalog number for Anti-SRGAP2 Antibody (C-term) is M05125-50ul.

What sizes are available for Anti-SRGAP2 Antibody (C-term)?

Anti-SRGAP2 Antibody (C-term) is available in the following size(s): 50 µL.

Is Anti-SRGAP2 Antibody (C-term) in stock?

Anti-SRGAP2 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SRGAP2 Antibody (C-term)?

The safety data sheet for Anti-SRGAP2 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=M05125.

What is Anti-SRGAP2 Antibody (C-term) used for?

Boster Bio Anti-SRGAP2 Antibody (C-term) (Catalog # M05125) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.