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Product details

Anti-GLS2 Antibody

Catalog number M05334-50ul

Price for M05334-50ul

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Size / count 50 µL

About this product

Boster Bio Anti-GLS2 Antibody (Catalog # M05334) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number
M05334-50ul
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Synonyms
Glutaminase liver isoform, mitochondrial, GLS, 3.5.1.2, L-glutaminase, L-glutamine amidohydrolase, GLS2, GA
Gene Name
GLS2
UniProt
Q9UI32
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This GLS2 antibody is generated from a mouse immunized with a recombinant protein of human GLS2.
Clonality
Monoclonal
Clone
Clone: 1758CT879.217.60
Tissue Specificity
Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
Applications
WB, IHC-P
Field of Research
Metabolism, Signal Transduction, Mitochondria
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha- ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
66323 Da
Subcellular Location
Mitochondrion.
Isotype
IgG1, k
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-GLS2 Antibody?

The catalog number for Anti-GLS2 Antibody is M05334-50ul.

What sizes are available for Anti-GLS2 Antibody?

Anti-GLS2 Antibody is available in the following size(s): 50 µL.

Is Anti-GLS2 Antibody in stock?

Anti-GLS2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GLS2 Antibody?

The safety data sheet for Anti-GLS2 Antibody is available here: https://www.bosterbio.com/msds?sku=M05334.

What is Anti-GLS2 Antibody used for?

Boster Bio Anti-GLS2 Antibody (Catalog # M05334) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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