Anti- (DANRE) srrt Antibody (C-Term)

Catalog number M05444-200ul

Price for M05444-200ul

Size / count 200 µL

About this product

Boster Bio Anti- (DANRE) srrt Antibody (C-Term) (Catalog # M05444) . Tested in WB application (s) . This antibody reacts with Human, Zebrafish.

Specifications

Catalog number: M05444-200ul
Size / count: 200 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity) . Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) .
Synonyms: Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2
Gene Name: Srrt
UniProt: Q66I22
Host: Rabbit
Reactivity: Human, Zebrafish
Immunogen: This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 733-766 amino acids from DANRE srrt.
Clonality: Polyclonal
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity) . Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) .
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 103274 Da
Applications Notes: WB: 1:2000
Subcellular Location: Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similarity) .
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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