Anti-REG3G Antibody

About this product

Boster Bio Anti-REG3G Antibody (Catalog # M05473) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number

M05473-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.

Synonyms

Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 16.5 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B

Gene Name

REG3G

UniProt

Q6UW15

Host

Mouse

Reactivity

Human

Immunogen

This REG3G antibody is generated from a mouse immunized with a recombinant protein of human REG3G.

Clonality

Monoclonal

Clone

Clone: 1790CT313.66.2

Tissue Specificity

Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta

Applications

WB, IHC-P

Field of Research

Inflammation, Immunology

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

19330 Da

Subcellular Location

Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854}

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.