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Product details

Anti-PURB Antibody (C-term)

Catalog number M06224-200ul

Price for M06224-200ul

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Size / count 200 µL

About this product

Boster Bio Anti-PURB Antibody (C-term) (Catalog # M06224) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number
M06224-200ul
Size / count
200 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Synonyms
Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
Gene Name
PURB
UniProt
Q96QR8
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.
Clonality
Monoclonal
Clone
Clone: 2117CT1176.48.6
Tissue Specificity
Expressed in myocardium of heart failure patients.
Applications
WB
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
33241 Da
Applications Notes
WB: 1:8000
Subcellular Location
Nucleus.
Prediction Reactivity
Human, Mouse
Isotype
IgG1, κ
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PURB Antibody (C-term)?

The catalog number for Anti-PURB Antibody (C-term) is M06224-200ul.

What sizes are available for Anti-PURB Antibody (C-term)?

Anti-PURB Antibody (C-term) is available in the following size(s): 200 µL.

Is Anti-PURB Antibody (C-term) in stock?

Anti-PURB Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PURB Antibody (C-term)?

The safety data sheet for Anti-PURB Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=M06224.

What is Anti-PURB Antibody (C-term) used for?

Boster Bio Anti-PURB Antibody (C-term) (Catalog # M06224) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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