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Product details

Anti-DKK2 Antibody

Catalog number M06431-50ul

Price for M06431-50ul

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Size / count 50 µL

About this product

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number
M06431-50ul
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Synonyms
Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2
Gene Name
DKK2
UniProt
Q9UBU2
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
Clonality
Monoclonal
Clone
Clone: 1833CT856.7.20
Tissue Specificity
Expressed in heart, brain, skeletal muscle and lung
Applications
WB
Field of Research
Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
28447 Da
Applications Notes
WB: 1:2000
Subcellular Location
Secreted.
Isotype
IgG1, k
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-DKK2 Antibody?

The catalog number for Anti-DKK2 Antibody is M06431-50ul.

What sizes are available for Anti-DKK2 Antibody?

Anti-DKK2 Antibody is available in the following size(s): 50 µL.

Is Anti-DKK2 Antibody in stock?

Anti-DKK2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DKK2 Antibody?

The safety data sheet for Anti-DKK2 Antibody is available here: https://www.bosterbio.com/msds?sku=M06431.

What is Anti-DKK2 Antibody used for?

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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