Anti-DKK2 Antibody

Catalog number M06431-200ul

Price for M06431-200ul

Size / count 200 µL

About this product

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: M06431-200ul
Size / count: 200 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Synonyms: Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2, DKK2
Gene Name: DKK2
UniProt: Q9UBU2
Host: Mouse
Reactivity: Human, Mouse
Immunogen: This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
Clonality: Monoclonal
Clone: Clone: 1833CT856.7.20
Tissue Specificity: Expressed in heart, brain, skeletal muscle and lung
Applications: WB
Field of Research: Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 28447 Da
Applications Notes: WB: 1:2000
Subcellular Location: Secreted.
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-DKK2 Antibody?

The catalog number for Anti-DKK2 Antibody is M06431-200ul.

What sizes are available for Anti-DKK2 Antibody?

Anti-DKK2 Antibody is available in the following size(s): 200 µL.

Is Anti-DKK2 Antibody in stock?

Anti-DKK2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DKK2 Antibody?

The safety data sheet for Anti-DKK2 Antibody is available here: https://www.bosterbio.com/msds?sku=M06431.

What is Anti-DKK2 Antibody used for?

Boster Bio Anti-DKK2 Antibody (Catalog # M06431) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.