Anti-H3f3b Antibody (C-Term)

Catalog number M06819-30-50ul

Price for M06819-30-50ul

Size / count 50 µL

About this product

Boster Bio Anti-H3f3b Antibody (C-Term) (Catalog # M06819-30) . Tested in WB application (s) . This antibody reacts with Mouse.

Specifications

Catalog number: M06819-30-50ul
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: Histone H33, H3f3a, H33a
Gene Name: H3-3a
UniProt: P84244
Host: Rabbit
Reactivity: Mouse
Immunogen: This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-136 amino acids from mouse H3f3b.
Clonality: Polyclonal
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 15328 Da
Applications Notes: WB: 1:2000
Subcellular Location: Nucleus. Chromosome.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-H3f3b Antibody (C-Term)?

The catalog number for Anti-H3f3b Antibody (C-Term) is M06819-30-50ul.

What sizes are available for Anti-H3f3b Antibody (C-Term)?

Anti-H3f3b Antibody (C-Term) is available in the following size(s): 50 µL.

Is Anti-H3f3b Antibody (C-Term) in stock?

Anti-H3f3b Antibody (C-Term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-H3f3b Antibody (C-Term)?

The safety data sheet for Anti-H3f3b Antibody (C-Term) is available here: https://www.bosterbio.com/msds?sku=M06819-30.

What is Anti-H3f3b Antibody (C-Term) used for?

Boster Bio Anti-H3f3b Antibody (C-Term) (Catalog # M06819-30) . Tested in WB application (s) . This antibody reacts with Mouse.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.