Anti-IL-34 Monoclonal Antibody

About this product

Boster Bio Anti-IL-34 Monoclonal Antibody catalog # M06903. Tested in WB, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number

M06903

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Interleukin-34; IL-34; IL34; C16orf77

Gene Name

IL34

UniProt

Q6ZMJ4

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of human IL-34 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 1D12

Tissue Specificity

Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level) . Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Applications

WB, IF, Flow Cytometry, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27482 MW

Gene Name Synonym

Interleukin-34

Subcellular Location

Secreted

Protein Name

Interleukin-34

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.