Anti-USP47 Antibody (Center)

About this product

Boster Bio Anti-USP47 Antibody (Center) (Catalog # M07648) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number

M07648-80ul

Size / count

80 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER) . Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level.

Synonyms

Ubiquitin carboxyl-terminal hydrolase 47, Deubiquitinating enzyme 47, Ubiquitin thioesterase 47, Ubiquitin-specific-processing protease 47, USP47

Gene Name

USP47

UniProt

Q96K76

Host

Rabbit

Reactivity

Human

Immunogen

This USP47 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 588-620 amino acids from the Central region of human USP47.

Clonality

Polyclonal

Tissue Specificity

Expressed in skeletal muscle, heart and testis.

Applications

WB, IHC-P

Field of Research

Cell Biology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER) . Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

157311 Da

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.