Product details

Anti-MKRN2 Antibody

Catalog number M10562-200ul

Price for M10562-200ul

Size / count 200 µL

About this product

Boster Bio Anti-MKRN2 Antibody (Catalog # M10562) . Tested in WB, Flow Cytometry, IHC-P, IF application (s) . This antibody reacts with Human.

Specifications

Catalog number: M10562-200ul
Size / count: 200 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Synonyms: Probable E3 ubiquitin-protein ligase makorin-2, 632-, RING finger protein 62, MKRN2, RNF62
Gene Name: MKRN2
UniProt: Q9H000
Host: Mouse
Reactivity: Human
Immunogen: This MKRN2 antibody is generated from a mouse immunized with recombinant protein.
Clonality: Monoclonal
Clone: Clone: 1556CT631.230.55.49
Tissue Specificity: Expressed in sperm, with significantly reduced expression in sperm of patients with oligoasthenoteratozoospermia (at protein level) (PubMed:28008940) . Widely expressed with expression in testis, ovary, small intestine, colon, peripheral blood leukocytes, fetal liver, bone marrow, thymus, lymph node and spleen (PubMed:11597136) .
Applications: WB, Flow Cytometry, IHC-P, IF
Field of Research: Cell Biology, Neuroscience
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity) . Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses (By similarity) . Plays a role in the regulation of spermiation and in male fertility (By similarity) .
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 46940 Da
Subcellular Location: Cytoplasm {ECO:0000250|UniProtKB:Q9ERV1}. Nucleus {ECO:0000250|UniProtKB:Q9ERV1}
Isotype: IgG1, k
Contents: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-MKRN2 Antibody?

The catalog number for Anti-MKRN2 Antibody is M10562-200ul.

What sizes are available for Anti-MKRN2 Antibody?

Anti-MKRN2 Antibody is available in the following size(s): 200 µL.

Is Anti-MKRN2 Antibody in stock?

Anti-MKRN2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MKRN2 Antibody?

The safety data sheet for Anti-MKRN2 Antibody is available here: https://www.bosterbio.com/msds?sku=M10562.

What is Anti-MKRN2 Antibody used for?

Boster Bio Anti-MKRN2 Antibody (Catalog # M10562) . Tested in WB, Flow Cytometry, IHC-P, IF application (s) . This antibody reacts with Human.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.