Anti-SOD2 Antibody

About this product

Boster Bio Anti-SOD2 Antibody (Catalog # M33970) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number

M33970-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Superoxide dismutase [Mn], mitochondrial, SOD2

Gene Name

SOD2

UniProt

P04179

Host

Mouse

Reactivity

Human

Immunogen

Purified His-tagged SOD protein (Fragment) was used to produced this monoclonal antibody.

Clonality

Monoclonal

Clone

Clone: 37CT127.5.11.6

Applications

WB, IHC-P

Field of Research

Cancer, Cardiovascular, Cell Biology, Metabolism, Neuroscience, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

24750 Da

Subcellular Location

Mitochondrion matrix.

Isotype

IgG1κ

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.