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Product details
Catalog number #30001
Price for #30001
Size / count 1x 1 mL
The loss of mitochondrial membrane potential is a hallmark for apoptosis. It is an early event preceding phosphatidylserine externalization and coinciding with caspase activation. JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells. In non-apoptotic cells, JC-1 accumulates as aggregates in the mitochondrial membranes, resulting in red fluorescence (590 nm) . The brightness of red fluorescence is proportional to the potential and varies among different cell types. However, in apoptotic and necrotic cells, which have diminished mitochondrial membrane potential, JC-1 exists in the green fluorescent (529 nm) monomeric form. This kit provides a step-by-step protocol and ready-to-use reagents for performing assays for flow cytometry, fluorescence microscopy, or fluorometric microplate reader.
The catalog number for JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is #30001.
JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is available in the following size(s): 1x 1 mL.
JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is currently made to order / not held in immediate stock. Contact us for lead time.
JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is manufactured by Biotium.
Estimated delivery time for JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is approximately 15 business day(s), depending on your location.
The safety data sheet for JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays) is available here: https://cdn.gentaur.com/products/37/699c39d20d8c9d341e164814/msds/%2330001.pdf.
The loss of mitochondrial membrane potential is a hallmark for apoptosis. It is an early event preceding phosphatidylserine externalization and coinciding with caspase activation. JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
