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Product details

BHMT Recombinant Mouse Monoclonal Antibody [9E1-R]

Catalog number HA601244

Price for HA601244

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Size / count 100 µL

About this product

Betaine-homocysteine methyltransferase (BHMT) is a zinc-dependent cytosolic protein that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. BHMT is highly expressed in rat liver, and its expression is regulated by dietary methionine and choline. In humans, S-adenosylmethionine (SAM) down-regulates BHMT expression by inducing NFκB, which acts as a repressor for the BHMT gene. Lowered BHMT levels can lead to ER (endoplasmic reticulum) stress. Mutations in the gene encoding for BHMT may lead to hyperhomocysteinemia, a medical condition characterized by abnormally large amounts of homocysteine in the blood which may be a risk factor for cardiovascular and cerebrovascular diseases.

Specifications

Catalog number
HA601244
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Betaine homocysteine methyltransferase antibody Betaine homocysteine S methyltransferase 1 antibody Betaine homocysteine S methyltransferase antibody Betaine--homocysteine S-methyltransferase 1 antibody BHMT antibody BHMT1 antibody BHMT1_HUMAN antibody EC 2.1.1.5 antibody Epididymis secretory sperm binding protein Li 61p antibody HEL S 61p antibody
Abbreviation
BHMT
Swiss Prot
Q93088 Human, 329582 Mouse, O09171 Rat
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein with Human BHMT aa 250-406 / 406.
Isotype
IgG1
Clone
9E1-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human kidney tissue lysate, human liver tissue lysate, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for BHMT Recombinant Mouse Monoclonal Antibody [9E1-R]?

The catalog number for BHMT Recombinant Mouse Monoclonal Antibody [9E1-R] is HA601244.

What sizes are available for BHMT Recombinant Mouse Monoclonal Antibody [9E1-R]?

BHMT Recombinant Mouse Monoclonal Antibody [9E1-R] is available in the following size(s): 100 µL.

Is BHMT Recombinant Mouse Monoclonal Antibody [9E1-R] in stock?

BHMT Recombinant Mouse Monoclonal Antibody [9E1-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is BHMT Recombinant Mouse Monoclonal Antibody [9E1-R] used for?

Betaine-homocysteine methyltransferase (BHMT) is a zinc-dependent cytosolic protein that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. BHMT is highly expressed in rat liver, and its expression is regulated by dietary methionine and choline. In

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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