Monoclonal Antibody to TLR6 (Clone: ABM1B50)

Catalog number 10-3002-100

Price for 10-3002-100

Size / count 100 µg

About this product

TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles) -induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression.

Specifications

Catalog number: 10-3002-100
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: No
Product Name Alternative: TLR6
Gene Name: TLR6
Gene ID: 10333
UniProt: Q9Y2C9
Host: Mouse
Reactivity: Human
Immunogen: A partial length recombinant TLR6 protein (amino acids 280-512) was used as the immunogen for this antibody.
Target Antigen: TLR6
Clonality: Monoclonal
Clone: ABM1B50
Applications: FACS, WB
Purification: Protein G Chromatography
Format: Purified
Components: 25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes: Western blot analysis: 2-4 μg/mL; FACS analysis: 0.5-1 μg/10^6 cells
Isotype: Mouse IgG1 Kappa

Frequently Asked Questions

What is the catalog number for Monoclonal Antibody to TLR6 (Clone: ABM1B50)?

The catalog number for Monoclonal Antibody to TLR6 (Clone: ABM1B50) is 10-3002-100.

What sizes are available for Monoclonal Antibody to TLR6 (Clone: ABM1B50)?

Monoclonal Antibody to TLR6 (Clone: ABM1B50) is available in the following size(s): 100 µg.

Is Monoclonal Antibody to TLR6 (Clone: ABM1B50) in stock?

Monoclonal Antibody to TLR6 (Clone: ABM1B50) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Monoclonal Antibody to TLR6 (Clone: ABM1B50) used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.