Monoclonal Antibody to TLR3 (Clone: ABM15D5)

Catalog number 10-3004-100

Price for 10-3004-100

Size / count 100 µg

About this product

TLR3 (Toll-Like Receptor-3) acts as a major receptor in virus-mediated innate immune response. This protein belongs to TLR (Toll-like receptor) family which comprises of 10-12 type I integral membrane receptor paralogs that recognize pathogen associated molecular signatures and initiate inflammatory responses. TLR3 consist of pathogen-binding ECD (Ectodomains) and cytoplasmic signaling domains, known as TIR (Toll IL-1 Receptor) domains, joined by a single transmembrane helix. TLR3 specifically senses dsRNA (Double-stranded RNA), an almost universal viral intermediate generated during most viral replications. TLR-3 activation induces multiple cellular antiviral responses, including production of IFN-alpha/beta and up-regulation of the anti-HIV cellular factor APOBEC3G. These are a family of pattern recognition receptors expressed by immune cells, including macrophages.

Specifications

Catalog number: 10-3004-100
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: No
Product Name Alternative: TLR3
Gene Name: TLR3
Gene ID: 7098
UniProt: O15455
Host: Mouse
Reactivity: Human
Immunogen: A partial length recombinant TLR3 protein (amino acids 25-370) was used as the immunogen for this antibody.
Target Antigen: TLR3
Clonality: Monoclonal
Clone: ABM15D5
Applications: FACS
Purification: Protein G Chromatography
Format: Purified
Components: 25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes: FACS analysis: 2.0 μg/10^6 cells
Isotype: Mouse IgG1 Kappa

Frequently Asked Questions

What is the catalog number for Monoclonal Antibody to TLR3 (Clone: ABM15D5)?

The catalog number for Monoclonal Antibody to TLR3 (Clone: ABM15D5) is 10-3004-100.

What sizes are available for Monoclonal Antibody to TLR3 (Clone: ABM15D5)?

Monoclonal Antibody to TLR3 (Clone: ABM15D5) is available in the following size(s): 100 µg.

Is Monoclonal Antibody to TLR3 (Clone: ABM15D5) in stock?

Monoclonal Antibody to TLR3 (Clone: ABM15D5) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Monoclonal Antibody to TLR3 (Clone: ABM15D5) used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.