PML Protein Rabbit Polyclonal Antibody

Catalog number HA500540

Price for HA500540

Size / count 100 µL

About this product

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear bodies, which form amongst the chromatin of the cell nucleus. These nuclear bodies are present in mammalian nuclei, at about 1 to 30 per cell nucleus. PML-NBs are known to have a number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division. PML mutation or loss, and the subsequent dysregulation of these processes, has been implicated in a variety of cancers.

Specifications

Catalog number: HA500540
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Acure promyelocytic leukemia, inducer of antibody MYL antibody Pml antibody PML_HUMAN antibody PP8675 antibody Probable transcription factor PML antibody Promyelocytic leukemia antibody Promyelocytic leukemia inducer of antibody Promyelocytic leukemia protein antibody Protein PML antibody RING finger protein 71 antibody RNF 71 antibody RNF71 antibody TRIM 19 antibody Tripartite motif protein TRIM19 antibody Tripartite motif-containing protein 19 antibody
Abbreviation: PML, MYL, PP8675, RNF71, TRIM19
Swiss Prot: P29590 Human, Q60953 Mouse,
Cellular Locus: Nucleus, Cytoplasm, PML body, nucleolus, Endoplasmic reticulum membrane, Early endosome membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human PML Protein aa 1-600 / 882.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: HeLa cell lysate, HEK-293 cell lysate, K-562 cell lysate, A549 cell lysate, MDA-MB-231 cell lysate, A431 cell lysate, human kidney tissue lysate, MDA-MB-231, A431, human brain tissue, human breast tissue, human breast cancer tissue, human testis tissue, mouse breast tissue, rat breast tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:1,000 ;FC: 1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 98 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PML Protein Rabbit Polyclonal Antibody?

The catalog number for PML Protein Rabbit Polyclonal Antibody is HA500540.

What sizes are available for PML Protein Rabbit Polyclonal Antibody?

PML Protein Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PML Protein Rabbit Polyclonal Antibody in stock?

PML Protein Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PML Protein Rabbit Polyclonal Antibody used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.