AF/LE Purified Anti-Human CD58 Antibody[TS2/9.1]

Specifications

Catalog number

E-AB-F10680-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI) -anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.

Abbreviation

CD58

Gene ID

965

UniProt

P19256

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD58 protein

Target

LFA; Ag3; CD58 antigen; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3; LFA3; CD58; LFA-3

Clonality

Monoclonal

Clone

TS2/9.1

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG1, κ