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Product details

Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml

Catalog number CRB2005004-01

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Price for CRB2005004-01

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Size / count 20 µg

About this product

<p dir="auto" data-start="502" data-end="926" class="PDq2pG_selectionAnchorContainer" style="text-align: justify;"><span data-start="502" data-end="888" style="">Anti-Peroxiredoxin SO2/3 antibody is a research antibody designed to detect the overoxidized forms of Peroxiredoxin proteins, particularly the SO₂/SO₃ forms of Peroxiredoxin 1–4. Peroxiredoxins are antioxidant enzymes involved in cellular peroxide metabolism and oxidative-stress responses. The antibody is supplied at approximately 0.24 mg/mL and is intended for research use only.</span> <span class="contents" data-content-reference-start="871" data-content-reference-end="890"><span class="" data-state="closed"></span></span><span aria-hidden="true" class="PDq2pG_selectionAnchor"></span></p>

Specifications

Catalog number
CRB2005004-01
Size / count
20 µg
Dry ice
No
Hazardous
No
Discontinued
No
Specifications
<div style="text-align: justify;"><strong data-start="1911" data-end="1948">Anti-Peroxiredoxin SO2/3 antibody</strong> is supplied under product code <strong data-start="1980" data-end="1994">CRB2005004</strong> at a concentration of approximately <strong data-start="2031" data-end="2045">0.24 mg/mL</strong>. The manufacturer identifies the antibody as <strong data-start="2091" data-end="2106">rabbit host</strong>, with reactivity against <strong data-start="2132" data-end="2150">human and frog</strong> targets. The antigen is a <strong data-start="2177" data-end="2213">KLH-conjugated synthetic peptide</strong>, and the antibody is supplied in <strong data-start="2247" data-end="2301">PBS containing 0.01% sodium azide and 1% trehalose</strong>. The manufacturer identifies the recognized protein type as <strong data-start="2362" data-end="2385">Peroxiredoxin SO2/3</strong>, corresponding to the overoxidized forms of Peroxiredoxin 1–4. The product is intended strictly for research purposes.</div>
Reactivity
<b>Species Reactivity</b><div><ul><li><strong data-start="5370" data-end="5379">Human</strong></li><li><strong data-start="5382" data-end="5390">Frog</strong></li></ul><b></b></div>
Target Antigen
<h2 data-section-id="5mkn7l" dir="auto" data-start="4981" data-end="5009" class="PDq2pG_selectionAnchorContainer"><b>Synthetic Peptide Antigen</b></h2><p dir="auto" data-start="5011" data-end="5194">The manufacturer identifies the antigen as a <strong data-start="5056" data-end="5092">KLH-conjugated synthetic peptide</strong>, rather than a recombinant full-length Peroxiredoxin protein.</p>
Target
<h2 data-section-id="1otklkp" dir="auto" data-start="2950" data-end="2979" class="PDq2pG_selectionAnchorContainer" style="text-align: justify;"><b>Overoxidized Peroxiredoxin</b></h2><p dir="auto" data-start="2981" data-end="3115" style="text-align: justify;">Peroxiredoxin proteins participate in cellular antioxidant defense by reducing hydrogen peroxide through cysteine-dependent reactions.</p><p dir="auto" data-start="3117" data-end="3392" style="text-align: justify;">When the catalytic cysteine undergoes further oxidation, the peroxidatic cysteine can form <strong data-start="3208" data-end="3232">sulfinic acid (SO₂H)</strong> or <strong data-start="3236" data-end="3260">sulfonic acid (SO₃H)</strong>. These overoxidized forms are associated with inactivation of the normal peroxidase activity. </p><p dir="auto" data-start="3394" data-end="3574" style="text-align: justify;">The antibody is therefore useful for research focused specifically on the <strong data-start="3468" data-end="3513">oxidation state of Peroxiredoxin proteins</strong>, rather than simply measuring total Peroxiredoxin abundance.</p><div style="text-align: justify;"><br></div>
Features & Benefits
<ul data-start="2565" data-end="2922"><li data-section-id="yu9vc1" data-start="2565" data-end="2606">Anti-Peroxiredoxin <strong data-start="2586" data-end="2597">SO₂/SO₃</strong> antibody<span aria-hidden="true" class="PDq2pG_selectionAnchor"></span> </li><li data-section-id="tt7ns3" data-start="2607" data-end="2646">Recognizes overoxidized Peroxiredoxin </li><li data-section-id="1vn9skl" data-start="2647" data-end="2697">Targets Peroxiredoxin <strong data-start="2671" data-end="2678">1–4</strong> overoxidized forms </li><li data-section-id="1efvt46" data-start="2698" data-end="2711">Rabbit host </li><li data-section-id="1fec4ca" data-start="2712" data-end="2739">Human and frog reactivity </li><li data-section-id="md9p2k" data-start="2740" data-end="2767">Synthetic peptide antigen </li><li data-section-id="17o1y4e" data-start="2768" data-end="2792">Approx. <strong data-start="2778" data-end="2792">0.24 mg/mL</strong> </li><li data-section-id="1m8c358" data-start="2793" data-end="2810">Supplied in PBS </li><li data-section-id="1qdvq8b" data-start="2811" data-end="2861">Contains <strong data-start="2822" data-end="2861">0.01% sodium azide and 1% trehalose</strong> </li><li data-section-id="85bup5" data-start="2862" data-end="2922">Research-use product <br></li></ul>
Shipping Conditions
Cool Pack
Controlled
No

Frequently Asked Questions

What is the catalog number for Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml?

The catalog number for Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml is CRB2005004.

What sizes are available for Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml?

Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml is available in the following size(s): 20 µg, 50 µg.

How many pack sizes does Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml come in?

Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml is available in 2 different pack sizes.

Is Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml in stock?

Anti-Peroxiredoxin SO2/3 antibody - 0.24mg/ml is currently made to order / not held in immediate stock. Contact us for lead time.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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