- Catalog number
- CRB2005004-01
- Size / count
- 20 µg
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Specifications
- <div style="text-align: justify;"><strong data-start="1911" data-end="1948">Anti-Peroxiredoxin SO2/3 antibody</strong> is supplied under product code <strong data-start="1980" data-end="1994">CRB2005004</strong> at a concentration of approximately <strong data-start="2031" data-end="2045">0.24 mg/mL</strong>. The manufacturer identifies the antibody as <strong data-start="2091" data-end="2106">rabbit host</strong>, with reactivity against <strong data-start="2132" data-end="2150">human and frog</strong> targets. The antigen is a <strong data-start="2177" data-end="2213">KLH-conjugated synthetic peptide</strong>, and the antibody is supplied in <strong data-start="2247" data-end="2301">PBS containing 0.01% sodium azide and 1% trehalose</strong>. The manufacturer identifies the recognized protein type as <strong data-start="2362" data-end="2385">Peroxiredoxin SO2/3</strong>, corresponding to the overoxidized forms of Peroxiredoxin 1–4. The product is intended strictly for research purposes.</div>
- Reactivity
- <b>Species Reactivity</b><div><ul><li><strong data-start="5370" data-end="5379">Human</strong></li><li><strong data-start="5382" data-end="5390">Frog</strong></li></ul><b></b></div>
- Target Antigen
- <h2 data-section-id="5mkn7l" dir="auto" data-start="4981" data-end="5009" class="PDq2pG_selectionAnchorContainer"><b>Synthetic Peptide Antigen</b></h2><p dir="auto" data-start="5011" data-end="5194">The manufacturer identifies the antigen as a <strong data-start="5056" data-end="5092">KLH-conjugated synthetic peptide</strong>, rather than a recombinant full-length Peroxiredoxin protein.</p>
- Target
- <h2 data-section-id="1otklkp" dir="auto" data-start="2950" data-end="2979" class="PDq2pG_selectionAnchorContainer" style="text-align: justify;"><b>Overoxidized Peroxiredoxin</b></h2><p dir="auto" data-start="2981" data-end="3115" style="text-align: justify;">Peroxiredoxin proteins participate in cellular antioxidant defense by reducing hydrogen peroxide through cysteine-dependent reactions.</p><p dir="auto" data-start="3117" data-end="3392" style="text-align: justify;">When the catalytic cysteine undergoes further oxidation, the peroxidatic cysteine can form <strong data-start="3208" data-end="3232">sulfinic acid (SO₂H)</strong> or <strong data-start="3236" data-end="3260">sulfonic acid (SO₃H)</strong>. These overoxidized forms are associated with inactivation of the normal peroxidase activity. </p><p dir="auto" data-start="3394" data-end="3574" style="text-align: justify;">The antibody is therefore useful for research focused specifically on the <strong data-start="3468" data-end="3513">oxidation state of Peroxiredoxin proteins</strong>, rather than simply measuring total Peroxiredoxin abundance.</p><div style="text-align: justify;"><br></div>
- Features & Benefits
- <ul data-start="2565" data-end="2922"><li data-section-id="yu9vc1" data-start="2565" data-end="2606">Anti-Peroxiredoxin <strong data-start="2586" data-end="2597">SO₂/SO₃</strong> antibody<span aria-hidden="true" class="PDq2pG_selectionAnchor"></span>
</li><li data-section-id="tt7ns3" data-start="2607" data-end="2646">Recognizes overoxidized Peroxiredoxin
</li><li data-section-id="1vn9skl" data-start="2647" data-end="2697">Targets Peroxiredoxin <strong data-start="2671" data-end="2678">1–4</strong> overoxidized forms
</li><li data-section-id="1efvt46" data-start="2698" data-end="2711">Rabbit host
</li><li data-section-id="1fec4ca" data-start="2712" data-end="2739">Human and frog reactivity
</li><li data-section-id="md9p2k" data-start="2740" data-end="2767">Synthetic peptide antigen
</li><li data-section-id="17o1y4e" data-start="2768" data-end="2792">Approx. <strong data-start="2778" data-end="2792">0.24 mg/mL</strong>
</li><li data-section-id="1m8c358" data-start="2793" data-end="2810">Supplied in PBS
</li><li data-section-id="1qdvq8b" data-start="2811" data-end="2861">Contains <strong data-start="2822" data-end="2861">0.01% sodium azide and 1% trehalose</strong>
</li><li data-section-id="85bup5" data-start="2862" data-end="2922">Research-use product <br></li></ul>
- Shipping Conditions
- Cool Pack
- Controlled
- No