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![Cannabinoid receptor 1 Recombinant Rabbit Monoclonal Antibody [PSH02-43] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea82063/imageurl/ha721820.webp)
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Product details
Catalog number HA721820
Price for HA721820
Size / count 100 µL
The endocannabinoid system consists of the cannabinoid receptors, CB1 and CB2 receptors, the enzymes that produce and degrade the endogenous cannabinoid ligands (such as FAAH, DAG lipases, and MAG lipase), and the endocannabinoid ligands derived from the metabolism of arachidonic acid, 2-arachidonoylglycerol (2-AG) and anandamide . CB1 receptor belongs to the superfamily of G protein-coupled receptors (GPCRs) and harbors a large N-terminal extracellular domain, seven transmembrane domains, and a C-terminal intracellular tail. CB1 receptor is coupled to the Gai/o subunit of the G protein which inhibits adenylyl cyclases and regulates calcium and potassium ion channels . CB1 receptor is one of the most abundant GPCRs in the central nervous system. It has been show to play critical roles in the wiring of the brain during development , in neuronal plasticity, analgesia, drug abuse and metabolic homeostasis (4). In addition, CB1 receptor has been shown to interact with other GPCRs, to give rise to novel pharmacological and signaling heteromers with implication in diseases .
The catalog number for Cannabinoid receptor 1 Recombinant Rabbit Monoclonal Antibody [PSH02-43] is HA721820.
Cannabinoid receptor 1 Recombinant Rabbit Monoclonal Antibody [PSH02-43] is available in the following size(s): 100 µL.
Cannabinoid receptor 1 Recombinant Rabbit Monoclonal Antibody [PSH02-43] is currently made to order / not held in immediate stock. Contact us for lead time.
The endocannabinoid system consists of the cannabinoid receptors, CB1 and CB2 receptors, the enzymes that produce and degrade the endogenous cannabinoid ligands (such as FAAH, DAG lipases, and MAG lipase), and the endocannabinoid ligands derived from the metabolism of arachidonic acid, 2-arachidonoy
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
