Caspase 1 Activity Detection Substrate for Flow Cytometry — image 1 of 3

Product details

Caspase 1 Activity Detection Substrate for Flow Cytometry

Catalog number E-CK-A481-01

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Price for E-CK-A481-01

Size / count 20 Tests

Specifications

Catalog number: E-CK-A481-01
Size / count: 20 Tests
Dry ice: No
Hazardous: No
Discontinued: No
Detection Method: Fluorometric method; Flow cytometry
Assay Principle: The Caspase 1 Activity Detection Substrate for Flow Cytometry are a novel fluorogenic dye that couple the caspase 1 recognition sequence (YVAD) to a high affinity DNA dye, which have cell membrane permeability and can penetrate the plasma membrane into the cytoplasm. The substrate itself has no fluorescence and has a charge exclusion effect with DNA. During cell apoptosis, caspase-1 cleaves the substrate and releases high affinity DNA dyes, which bind to DNA to produce strong fluorescence, thereby detecting caspase-1 activity and visualizing the morphological changes of the cell nucleus during apoptosis.
Sample Type: Cell samples
Shipping Conditions: Ice bag
Storage Conditions: This product can be stored at -20°C for 1 year in the dark.
Detection Instrument: Flow Cytometer; Fluorescence microscope

Frequently Asked Questions

What is the catalog number for Caspase 1 Activity Detection Substrate for Flow Cytometry?

The catalog number for Caspase 1 Activity Detection Substrate for Flow Cytometry is E-CK-A481.

What sizes are available for Caspase 1 Activity Detection Substrate for Flow Cytometry?

Caspase 1 Activity Detection Substrate for Flow Cytometry is available in the following size(s): 20 Tests, 100 Tests.

How many pack sizes does Caspase 1 Activity Detection Substrate for Flow Cytometry come in?

Caspase 1 Activity Detection Substrate for Flow Cytometry is available in 2 different pack sizes.

Is Caspase 1 Activity Detection Substrate for Flow Cytometry in stock?

Caspase 1 Activity Detection Substrate for Flow Cytometry is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caspase 1 Activity Detection Substrate for Flow Cytometry?

Caspase 1 Activity Detection Substrate for Flow Cytometry is manufactured by Elabscience.

What is the estimated delivery time for Caspase 1 Activity Detection Substrate for Flow Cytometry?

Estimated delivery time for Caspase 1 Activity Detection Substrate for Flow Cytometry is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caspase 1 Activity Detection Substrate for Flow Cytometry?

The safety data sheet for Caspase 1 Activity Detection Substrate for Flow Cytometry is available here: https://789.bio/eb/9he9OR.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.