Product details
Catalog number HA721667
Price for HA721667
Size / count 100 µL
The tau proteins (abbreviated from tubulin associated unit are a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in the neurons of the central nervous system (CNS), where the cerebral cortex has the highest abundance. They are less common elsewhere but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become hyperphosphorylated insoluble aggregates called neurofibrillary tangles. The tau proteins were identified in 1975 as heat-stable proteins essential for microtubule assembly, and since then they have been characterized as intrinsically disordered proteins.
The catalog number for Phospho-Tau (S199) Recombinant Rabbit Monoclonal Antibody [JE66-80] is HA721667.
Phospho-Tau (S199) Recombinant Rabbit Monoclonal Antibody [JE66-80] is available in the following size(s): 100 µL.
Phospho-Tau (S199) Recombinant Rabbit Monoclonal Antibody [JE66-80] is currently made to order / not held in immediate stock. Contact us for lead time.
The tau proteins (abbreviated from tubulin associated unit are a group of six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant in
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
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