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Product details

Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]

Catalog number E-AB-F1072M1-01

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Price for E-AB-F1072M1-01

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Size / count 20 Tests

Specifications

Catalog number
E-AB-F1072M1-01
Size / count
20 Tests
Dry ice
No
Hazardous
No
Discontinued
No
Background
CD74 is a type II transmembrane glycoprotein also known as MHC class II associated invariant chain, invariant chain, Ii, MHC class II chaperone, and MIF receptor. CD74 exists in four isoforms with molecular masses of 33, 35, 41, and 43 kD, depending on genetic splicing. CD74 is primarily expressed on antigen presenting cells, including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells. It is also expressed by activated T cells and activated endothelial and epithelial cells as well as carcinomas of lung, renal, gastric and thymic origin. The primary function of CD74 is intracellular sorting of MHC class II molecules and regulation of exogenous peptide loading onto MHC class II. It is also involved in the modulation of B cell differentiation and positive selection of CD4+ T cells. It has been reported that CD74 binds MIF (macrophage migration inhibitory factor) and signals through CD44 to regulate innate and adaptive immunity. It is also reported that H. pylori infection occurs through urease B binding of CD74 on gastric epithelial cells, inducing gastric epithelial cell apoptosis, NF-κB activation, and IL-8 production.
Abbreviation
CD74
Gene ID
972
UniProt
P04233
Host
Mouse
Reactivity
Human
Target
CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; Ia antigen-associated invariant chain; Ii; p33
Clonality
Monoclonal
Clone
LN2
Conjugation
Elab Fluor®700
Applications
FCM
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ

Frequently Asked Questions

What is the catalog number for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]?

The catalog number for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is E-AB-F1072M1.

What sizes are available for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]?

Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is available in the following size(s): 20 Tests, 100 Tests, 2x 100 Tests.

How many pack sizes does Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] come in?

Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is available in 3 different pack sizes.

Is Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] in stock?

Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]?

Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is manufactured by Elabscience.

What is the estimated delivery time for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]?

Estimated delivery time for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2]?

The safety data sheet for Elab Fluor® 700 Anti-Human CD74 Antibody[LN2] is available here: https://789.bio/eb/84VLh5.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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