ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53]

Catalog number HA721829

Price for HA721829

Size / count 100 µL

About this product

Cysteine protease ATG4B is an enzyme that in humans is encoded by the ATG4B gene. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. One main function of Atg4 is to cleave the pre-protein of Atg8, leading to the non-lipidated soluble (-I) form which can be processed further by Atg3, Atg7, Atg5-12 into the lipidated form (-II) anchored to the autophagic membrane.

Specifications

Catalog number: HA721829
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: APG4 autophagy 4 homolog B antibody APG4B antibody ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody ATG4B antibody ATG4B_HUMAN antibody AUT like 1 cysteine endopeptidase antibody AUT-like 1 cysteine endopeptidase antibody AUTL1 antibody Autophagin 1 antibody Autophagin-1 antibody Autophagy related 4B cysteine peptidase antibody Autophagy related cysteine endopeptidase 1 antibody Autophagy related protein 4 homolog B antibody Autophagy-related cysteine endopeptidase 1 antibody Autophagy-related protein 4 homolog B antibody Cysteine protease ATG4B antibody hAPG4B antibody MGC1353 antibody
Abbreviation: ATG4B, APG4B, AUTL1, KIAA0943
Swiss Prot: Q9Y4P1 Human, Q8BGE6 Mouse, Q62625 Rat
Cellular Locus: Cytoplasm, cytosol, Cytoplasmic vesicle, autophagosome, Endoplasmic reticulum, Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat, Monkey
Immunogen: Recombinant protein within human ATG4B aa 1-393 / 393 (Q9Y4P1).
Isotype: IgG
Clone: PSH02-53
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: HeLa cell lysate, Jurkat cell lysate, 293T cell lysate, MCF7 cell lysate, K-562 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, PC-12 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, Mouse kidney tissue lysate, Mouse colon tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 44 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53]?

The catalog number for ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53] is HA721829.

What sizes are available for ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53]?

ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53] is available in the following size(s): 100 µL.

Is ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53] in stock?

ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATG4B Recombinant Rabbit Monoclonal Antibody [PSH02-53] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.