HADHA Recombinant Rabbit Monoclonal Antibody [PSH01-28]

About this product

Trifunctional enzyme subunit alpha, mitochondrial also known as hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit is a protein that in humans is encoded by the HADHA gene. Mutations in HADHA have been associated with trifunctional protein deficiency or long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The enzyme converts medium- and long-chain 2-enoyl-CoA compounds into the following 3-ketoacyl-CoA when NAD is solely present, and acetyl-CoA when NAD and CoASH are present. The alpha subunit catalyzes this reaction, and is attached to HADHB, which catalyzes the last step of the reaction.

Specifications

Catalog number

HA721652

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

3 ketoacyl Coenzyme A (CoA) thiolase alpha subunit antibody 3 oxoacyl CoA thiolase antibody 78 kDa gastrin binding protein antibody 78 kDa gastrin-binding protein antibody ECHA antibody ECHA_HUMAN antibody GBP antibody HADH antibody HADHA antibody Hydroxyacyl Coenzyme A dehydrogenase/3 ketoacyl Coenzyme A thiolase/enoyl Coenzyme A hydratase (trifunctional protein) alpha subunit antibody LCEH antibody LCHAD antibody Long chain 3-hydroxyacyl-CoA dehydrogenase antibody Mitochondrial long chain 2 enoyl Coenzyme A (CoA) hydratase alpha subunit antibody Mitochondrial long chain L 3 hydroxyacyl Coenzyme A dehydrogenase alpha subunit antibody Mitochondrial trifunctional enzyme alpha subunit antibody Mitochondrial trifunctional protein alpha subunit antibody MTPA antibody Thiolase/enoyl Coenzyme A hydratase (trifunctional protein) alpha subunit antibody TP ALPHA antibody TP-alpha antibody Trifunctional enzyme subunit alpha mitochondrial precursor antibody

Abbreviation

HADHA, HADH

Swiss Prot

P40939 Human, Q8BMS1 Mouse, Q64428 Rat

Cellular Locus

Mitochondrion, Mitochondrion inner membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Recombinant protein within human HADHA aa 1-763 / 763.

Isotype

IgG

Clone

PSH01-28

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

293T cell lysate, HeLa cell lysate, HepG2 cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, COS-1 cell lysate, mouse heart tissue lysate, mouse kidney tissue lysate, human kidney tissue lysate, rat liver tissue lysate, HeLa, human heart tissue, human kidney tissue, mouse heart tissue, mouse kidney tissue, rat heart tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 83 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes