Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76]

Catalog number HA722892

Price for HA722892

Size / count 100 µL

About this product

The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. It is the first member of a family of endocytic receptors that includes Endo180 (CD280), M-type PLA2R, and DEC-205 (CD205). The receptor recognises terminal mannose, N-acetylglucosamine and fucose residues on glycans attached to proteins found on the surface of some microorganisms, playing a role in both the innate and adaptive immune systems. Additional functions include clearance of glycoproteins from circulation, including sulphated glycoprotein hormones and glycoproteins released in response to pathological events. The mannose receptor recycles continuously between the plasma membrane and endosomal compartments in a clathrin-dependent manner.

Specifications

Catalog number: HA722892
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: bA541I19.1 antibody C type lectin domain family 13 member D antibody C-type lectin domain family 13 member D antibody CD 206 antibody CD206 antibody CD206 antigen antibody CLEC13D antibody CLEC13DL antibody Macrophage mannose receptor 1 antibody Macrophage mannose receptor 1 like protein 1 antibody Macrophage mannose receptor antibody Mannose receptor C type 1 antibody Mannose receptor C type 1 like 1 antibody MMR antibody MRC 1 antibody MRC1 antibody MRC1_HUMAN antibody MRC1L1 antibody OTTHUMP00000045206 antibody
Abbreviation: Mrc1
Swiss Prot: Q61830 Mouse,
Cellular Locus: Endosome membrane, Cell membrane.
Host: Rabbit
Species Reactivity: Mouse, Rat
Immunogen: Recombinant protein within mouse Mannose Receptor (CD206) aa 1-1,409.
Isotype: IgG
Clone: PSH07-76
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Tissue, IHC-Fr, IF-Cell, IP
Positive Control: RAW264.7 treated with 20ng/mL mIL-4 and 10ng/mL mIL-13 for 24 hours cell lysate, Mouse lung tissue lysate, Mouse spleen tissue lysate, Rat brain tissue lysate, Rat lung tissue lysate, Rat liver tissue lysate, mouse spleen tissue, mouse liver tissue, rat liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:500 ;IHC-Fr: 1:500 ;IF-Cell: 1:50 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 165 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76]?

The catalog number for Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76] is HA722892.

What sizes are available for Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76]?

Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76] is available in the following size(s): 100 µL.

Is Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76] in stock?

Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76] used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.