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Product details

Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93]

Catalog number HA721912

Price for HA721912

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Size / count 100 µL

About this product

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis . Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation. Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation. Anchors the lamina and the heterochromatin to the inner nuclear membrane.

Specifications

Catalog number
HA721912
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DHCR 14B antibody DHCR14B antibody Integral nuclear envelope inner membrane protein antibody Lamin-B receptor antibody LBR antibody LBR_HUMAN antibody LMN 2R antibody LMN2R antibody MGC9041 antibody PHA antibody PRO0650 antibody
Abbreviation
Delta-14-SR 3-beta-hydroxysterol Delta (14)-reductase 1 Publication C-14 sterol reductase (C14SR) Integral nuclear envelope inner membrane protein 1 Publication LMN2R Lamin-B receptor 2 Publications Sterol C14-reductase
Swiss Prot
Q14739 Human
Cellular Locus
Nucleus inner membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Lamin B Receptor/LBR aa 1-500 / 615.
Isotype
IgG
Clone
PSH02-93
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HEK-293 cell lysate, HeLa cell lysate, Jurkat cell lysate, HEK-293, human small intestine tissue, human testis tissue.
Concentration
1 mg/mL
Dilution
WB:1:2,000 ;IHC-P:1:1,000-10,000 ;IF-Cell:1:2,000 ;FC:1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 71 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93]?

The catalog number for Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93] is HA721912.

What sizes are available for Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93]?

Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93] is available in the following size(s): 100 µL.

Is Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93] in stock?

Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93] used for?

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis . Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation. Mediates the activation o

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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