• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00]

Catalog number HA722070

Price for HA722070

Sign In for Pricing

Size / count 100 µL

About this product

Sortilin (SORT1) is a protein that in humans is encoded by the SORT1 gene on chromosome 1. This protein is a type I membrane glycoprotein in the vacuolar protein sorting 10 protein (Vps10p) family of sorting receptors. While it is ubiquitously expressed in many tissues, sortilin is most abundant in the central nervous system. At the cellular level, sortilin functions in protein transport between the Golgi apparatus, endosome, lysosome, and plasma membrane, leading to its involvement in multiple biological processes such as glucose and lipid metabolism as well as neural development and cell death. Moreover, the function and role of sortilin is now emerging in several major human diseases such as hypertension, atherosclerosis, coronary artery disease, Alzheimer’s disease, and cancer. The SORT1 gene also contains one of 27 loci associated with increased risk of coronary artery disease.

Specifications

Catalog number
HA722070
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
100 kDa NT receptor antibody Glycoprotein 95 antibody Gp 95 antibody Gp95 antibody LDLCQ6 antibody Neurotensin receptor 3 antibody NT 3 antibody NT3 antibody NTR 3 antibody NTR3 antibody OTTHUMP00000013784 antibody SORT 1 antibody SORT_HUMAN antibody SORT1 (gene name) antibody Sort1 antibody Sortilin 1 antibody Sortilin antibody
Abbreviation
SORT1
Swiss Prot
Q99523 Human
Cellular Locus
Golgi apparatus, Golgi stack membrane, Endosome membrane, Endoplasmic reticulum membrane, Nucleus membrane, Cell membrane, Lysosome membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human Sortilin aa 601-800 / 831.
Isotype
IgG
Clone
JE60-00
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
SK-MEL-28 cell lysate, human lung tissue lysate, human kidney tissue lysate, human liver tissue lysate, SH-SY5Y cell lysate, human brain tissue lysate, human brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 92 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00]?

The catalog number for Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00] is HA722070.

What sizes are available for Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00]?

Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00] is available in the following size(s): 100 µL.

Is Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00] in stock?

Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Sortilin Recombinant Rabbit Monoclonal Antibody [JE60-00] used for?

Sortilin (SORT1) is a protein that in humans is encoded by the SORT1 gene on chromosome 1. This protein is a type I membrane glycoprotein in the vacuolar protein sorting 10 protein (Vps10p) family of sorting receptors. While it is ubiquitously expressed in many tissues, sortilin is most abundant in

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

You Might Also Like
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880460-100
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880177-100
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680039-100
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400178-500
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740468-100
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040956-500
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940807-100