Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector)

Catalog number HA601196

Price for HA601196

Size / count 100 µg

About this product

IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.

Specifications

Catalog number: HA601196
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CVID11 antibody IL 21 antibody IL-21 antibody Il21 antibody IL21_HUMAN antibody Interleukin 21 antibody Interleukin-21 antibody interleukin-21 isoform antibody Interleukin21 antibody OTTHUMP00000164088 antibody Za11 antibody
Abbreviation: Interleukin-21 IL-21 Za11 IL21
Swiss Prot: Q9HBE4 Human
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human IL-21 aa 25-162 (Q9HBE4).
Isotype: IgG1
Clone: PSH02-49
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: ELISA (Det)
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [PSH02-48] to Human IL-21 (Capture) (HA601195).
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Molecular Weight: Predicted band size: 18.6 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector)?

The catalog number for Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector) is HA601196.

What sizes are available for Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector)?

Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector) is available in the following size(s): 100 µg.

Is Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector) in stock?

Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-21 Recombinant Mouse Monoclonal Antibody [PSH02-49] - BSA and Azide free (Detector) used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.